Gulfstream Daily Brief

Regulatory intelligence and policy · Issue 003

FDA opens botanical drug docket, MHRA and EMA publish regulatory resources

Today’s brief covers FDA’s request for information on botanical drug development, plus UK and EU resources on real world evidence, licensing pathways and adverse reaction data.

By Scott Morvay, Founder September 4, 2026 Official sources linked

FDA

FDA seeks input on botanical drug development

FDA opened a public docket requesting stakeholder perspectives on botanical drug development in the United States, including challenges and potential solutions for gathering information required under the FD&C Act.

Read the official source

MHRA

MHRA and NICE describe real world evidence dialogue

The agencies published information on a scientific dialogue programme intended to support decision making across product lifecycles and inform regulatory and health technology assessment evaluations.

Read the official source

MHRA

MHRA publishes International Recognition Procedure guidance

The guidance explains how to use the International Recognition Procedure for medicines licensing applications.

Read the official source

EMA

EMA issues EudraVigilance portal user manual

EMA published version 2.2 of its user manual for online access to suspected adverse reaction information through the adrreports.eu portal.

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MHRA

MHRA provides medicine reclassification guidance

The guidance explains how to apply to move a medicine among pharmacy, prescription only and general sale list classifications.

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Why this matters

The FDA docket offers stakeholders a formal route to describe evidence challenges in botanical drug development. In Europe, the MHRA and EMA materials provide practical references for evidence planning, licensing, medicine classification and access to adverse reaction reports.

Scott Morvay

Founder, Gulfstream Intelligence

This brief provides general regulatory news and educational information. It is not legal or regulatory advice.